Nuclear Export in Non-Hodgkin Lymphoma and Implications for Targeted XPO1 Inhibitors

Exportin-1 (XPO1) is a key player in the nuclear export pathway and is overexpressed in almost all cancers. This is especially relevant for non-Hodgkin lymphoma (NHL), where high XPO1 expression is associated with poor prognosis due to its oncogenic role in exporting proteins and RNA that are involv...

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Detalles Bibliográficos
Autores principales: Trkulja, Kyla L., Manji, Farheen, Kuruvilla, John, Laister, Rob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855521/
https://www.ncbi.nlm.nih.gov/pubmed/36671496
http://dx.doi.org/10.3390/biom13010111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855521/
https://www.ncbi.nlm.nih.gov/pubmed/36671496
http://dx.doi.org/10.3390/biom13010111

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