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Nuclear Export in Non-Hodgkin Lymphoma and Implications for Targeted XPO1 Inhibitors

Exportin-1 (XPO1) is a key player in the nuclear export pathway and is overexpressed in almost all cancers. This is especially relevant for non-Hodgkin lymphoma (NHL), where high XPO1 expression is associated with poor prognosis due to its oncogenic role in exporting proteins and RNA that are involv...

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Detalles Bibliográficos
Autores principales:	Trkulja, Kyla L., Manji, Farheen, Kuruvilla, John, Laister, Rob C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855521/ https://www.ncbi.nlm.nih.gov/pubmed/36671496 http://dx.doi.org/10.3390/biom13010111

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