Approaches and Vectors for Efficient Cochlear Gene Transfer in Adult Mouse Models

Inner ear gene therapy using adeno-associated viral vectors (AAVs) in neonatal mice can alleviate hearing loss in mouse models of deafness. However, efficient and safe transgene delivery to the adult mouse cochlea is critical for the effectiveness of AAV-mediated therapy. Here, we examined three gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yu, Zhang, Longlong, Wang, Daqi, Chen, Bing, Shu, Yilai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855574/
https://www.ncbi.nlm.nih.gov/pubmed/36671423
http://dx.doi.org/10.3390/biom13010038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855574/
https://www.ncbi.nlm.nih.gov/pubmed/36671423
http://dx.doi.org/10.3390/biom13010038

Ejemplares similares