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Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice

7DW8-5 is a potent glycolipid adjuvant that improves malaria vaccine efficacy in mice by inducing IFN-γ and increasing protective CD8(+) T cell responses. The addition of 7DW8-5 was previously shown to improve the efficacy of a CD8(+) T cell-mediated heterologous ‘prime-and-trap’ malaria vaccine aga...

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Detalles Bibliográficos
Autores principales: Watson, Felicia N., Duncombe, Caroline J., Kalata, Anya C., Conrad, Ethan, Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., Tsuji, Moriya, Shears, Melanie J., Murphy, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855660/
https://www.ncbi.nlm.nih.gov/pubmed/36671393
http://dx.doi.org/10.3390/biom13010008