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Patisiran Enhances Muscle Mass after Nine Months of Treatment in ATTRv Amyloidosis: A Study with Bioelectrical Impedance Analysis and Handgrip Strength

Background and aims. Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv) is caused by mutations in the TTR gene, leading to misfolded monomers that aggregate generating amyloid fibrils. The clinical phenotype is heterogeneous, characterized by a multisystemic disease affecting the senso...

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Detalles Bibliográficos
Autores principales: Di Stefano, Vincenzo, Thomas, Ewan, Alonge, Paolo, Giustino, Valerio, Pillitteri, Guglielmo, Leale, Ignazio, Torrente, Angelo, Pignolo, Antonia, Norata, Davide, Iacono, Salvatore, Lupica, Antonino, Palma, Antonio, Battaglia, Giuseppe, Brighina, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855676/
https://www.ncbi.nlm.nih.gov/pubmed/36672570
http://dx.doi.org/10.3390/biomedicines11010062