Druggable Pockets at the RNA Interface Region of Influenza A Virus NS1 Protein Are Conserved across Sequence Variants from Distinct Subtypes

Influenza A viruses still represent a major health issue, for both humans and animals. One of the main viral proteins of interest to target is the NS1 protein, which counters the host immune response and promotes viral replication. NS1 is a homodimer composed of a dimeric RNA-binding domain (RBD), w...

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Detalles Bibliográficos
Autores principales: Naceri, Sarah, Marc, Daniel, Blot, Rachel, Flatters, Delphine, Camproux, Anne-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855689/
https://www.ncbi.nlm.nih.gov/pubmed/36671449
http://dx.doi.org/10.3390/biom13010064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855689/
https://www.ncbi.nlm.nih.gov/pubmed/36671449
http://dx.doi.org/10.3390/biom13010064

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