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Druggable Pockets at the RNA Interface Region of Influenza A Virus NS1 Protein Are Conserved across Sequence Variants from Distinct Subtypes
Influenza A viruses still represent a major health issue, for both humans and animals. One of the main viral proteins of interest to target is the NS1 protein, which counters the host immune response and promotes viral replication. NS1 is a homodimer composed of a dimeric RNA-binding domain (RBD), w...
Autores principales: | Naceri, Sarah, Marc, Daniel, Blot, Rachel, Flatters, Delphine, Camproux, Anne-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855689/ https://www.ncbi.nlm.nih.gov/pubmed/36671449 http://dx.doi.org/10.3390/biom13010064 |
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