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Considerations for Applying Route-to-Route Extrapolation to Assess the Safety of Oral Exposure to Substances
The safety evaluation of oral exposure to substances, such as food ingredients, additives, and their constituents, relies primarily on a careful evaluation and analysis of data from oral toxicity studies. When relevant oral toxicity studies are unavailable or may have significant data gaps that make...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855723/ https://www.ncbi.nlm.nih.gov/pubmed/36671390 http://dx.doi.org/10.3390/biom13010005 |