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Functional Gene Expression Signatures from On-Treatment Tumor Specimens Predict Anti-PD1 Blockade Response in Metastatic Melanoma

Functional gene expression signatures (FGES) from pretreatment biopsy samples have been used to predict the responses of metastatic melanoma to immune checkpoint blockade (ICB) therapies. However, there are no predictive FGE signatures from patients receiving treatment. Here, using the Elastic Net R...

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Detalles Bibliográficos
Autores principales: Chen, Shuzhao, Zhang, Limei, Lin, Haocheng, Liang, Yang, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855743/
https://www.ncbi.nlm.nih.gov/pubmed/36671443
http://dx.doi.org/10.3390/biom13010058