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Escape from Cellular Senescence Is Associated with Chromosomal Instability in Oral Pre-Malignancy

SIMPLE SUMMARY: Cancer cells commonly escape cell death and proliferate endlessly. We review the molecular mechanisms that are fundamental to this process and suggest that these changes also lead to instability in the genetic make-up (genes and chromosomes) of putative cancer cells. In this way, cel...

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Detalles Bibliográficos
Autores principales: Prime, Stephen S., Cirillo, Nicola, Parkinson, E. Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855962/
https://www.ncbi.nlm.nih.gov/pubmed/36671795
http://dx.doi.org/10.3390/biology12010103