Inactive Proteasomes Routed to Autophagic Turnover Are Confined within the Soluble Fraction of the Cell

Previous studies demonstrated that dysfunctional yeast proteasomes accumulate in the insoluble protein deposit (IPOD), described as the final deposition site for amyloidogenic insoluble proteins and that this compartment also mediates proteasome ubiquitination, a prerequisite for their targeted auto...

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Detalles Bibliográficos
Autores principales: Friedman, Keren, Karmon, Ofri, Fridman, Uri, Goldberg, Yair, Pines, Ophry, Ben-Aroya, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855985/
https://www.ncbi.nlm.nih.gov/pubmed/36671462
http://dx.doi.org/10.3390/biom13010077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855985/
https://www.ncbi.nlm.nih.gov/pubmed/36671462
http://dx.doi.org/10.3390/biom13010077

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