Inhibition of PDE10A in a New Rat Model of Severe Dopamine Depletion Suggests New Approach to Non-Dopamine Parkinson’s Disease Therapy

Parkinson’s disease is the second most common neurodegenerative pathology. Due to the limitations of existing therapeutic approaches, novel anti-parkinsonian medicines with non-dopamine mechanisms of action are clearly needed. One of the promising pharmacological targets for anti-Parkinson drug deve...

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Detalles Bibliográficos
Autores principales: Sukhanov, Ilya, Dorotenko, Artem, Fesenko, Zoia, Savchenko, Artem, Efimova, Evgeniya V., Mor, Mikael S., Belozertseva, Irina V., Sotnikova, Tatyana D., Gainetdinov, Raul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855999/
https://www.ncbi.nlm.nih.gov/pubmed/36671394
http://dx.doi.org/10.3390/biom13010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855999/
https://www.ncbi.nlm.nih.gov/pubmed/36671394
http://dx.doi.org/10.3390/biom13010009

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