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Inhibition of PDE10A in a New Rat Model of Severe Dopamine Depletion Suggests New Approach to Non-Dopamine Parkinson’s Disease Therapy
Parkinson’s disease is the second most common neurodegenerative pathology. Due to the limitations of existing therapeutic approaches, novel anti-parkinsonian medicines with non-dopamine mechanisms of action are clearly needed. One of the promising pharmacological targets for anti-Parkinson drug deve...
Autores principales: | Sukhanov, Ilya, Dorotenko, Artem, Fesenko, Zoia, Savchenko, Artem, Efimova, Evgeniya V., Mor, Mikael S., Belozertseva, Irina V., Sotnikova, Tatyana D., Gainetdinov, Raul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855999/ https://www.ncbi.nlm.nih.gov/pubmed/36671394 http://dx.doi.org/10.3390/biom13010009 |
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