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Persulfidation of DJ-1: Mechanism and Consequences

DJ-1 (also called PARK7) is a ubiquitously expressed protein involved in the etiology of Parkinson disease and cancers. At least one of its three cysteine residues is functionally essential, and its oxidation state determines the specific function of the enzyme. DJ-1 was recently reported to be pers...

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Detalles Bibliográficos
Autores principales: Galardon, Erwan, Mathas, Nicolas, Padovani, Dominique, Le Corre, Laurent, Poncet, Gabrielle, Dairou, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856005/
https://www.ncbi.nlm.nih.gov/pubmed/36671412
http://dx.doi.org/10.3390/biom13010027