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Targeting Features of Curaxin CBL0137 on Hematological Malignancies In Vitro and In Vivo

The anticancer activity of Curaxin CBL0137, a DNA-binding small molecule with chromatin remodulating effect, has been demonstrated in different cancers. Herein, a comparative evaluation of CBL0137 activity was performed in respect to acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL),...

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Detalles Bibliográficos
Autores principales: Fetisov, Timur I., Borunova, Anna A., Antipova, Alina S., Antoshina, Elena E., Trukhanova, Lubov S., Gorkova, Tatyana G., Zuevskaya, Svetlana N., Maslov, Alexei, Gurova, Katerina, Gudkov, Andrei, Lesovaya, Ekaterina A., Belitsky, Gennady A., Yakubovskaya, Marianna G., Kirsanov, Kirill I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856019/
https://www.ncbi.nlm.nih.gov/pubmed/36672738
http://dx.doi.org/10.3390/biomedicines11010230