Heparin-Induced Changes of Vascular Endothelial Growth Factor (VEGF(165)) Structure

Vascular endothelial growth factor-A (VEGF-A), a secreted homodimeric glycoprotein, is a critical regulator of angiogenesis in normal and pathological states. The binding of heparin (HE) to VEGF(165) (the major form of VEGF-A) modulates the angiogenesis-related cascade, but the mechanism of the obse...

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Detalles Bibliográficos
Autores principales: Nemashkalova, Ekaterina L., Shevelyova, Marina P., Machulin, Andrey V., Lykoshin, Dmitry D., Esipov, Roman S., Deryusheva, Evgenia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856036/
https://www.ncbi.nlm.nih.gov/pubmed/36671483
http://dx.doi.org/10.3390/biom13010098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856036/
https://www.ncbi.nlm.nih.gov/pubmed/36671483
http://dx.doi.org/10.3390/biom13010098

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