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Heparin-Induced Changes of Vascular Endothelial Growth Factor (VEGF(165)) Structure
Vascular endothelial growth factor-A (VEGF-A), a secreted homodimeric glycoprotein, is a critical regulator of angiogenesis in normal and pathological states. The binding of heparin (HE) to VEGF(165) (the major form of VEGF-A) modulates the angiogenesis-related cascade, but the mechanism of the obse...
Autores principales: | Nemashkalova, Ekaterina L., Shevelyova, Marina P., Machulin, Andrey V., Lykoshin, Dmitry D., Esipov, Roman S., Deryusheva, Evgenia I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856036/ https://www.ncbi.nlm.nih.gov/pubmed/36671483 http://dx.doi.org/10.3390/biom13010098 |
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