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Network-Based Assessment of Minimal Change Disease Identifies Glomerular Response to IL-7 and IL-12 Pathways Activation as Innovative Treatment Target

Background: Minimal change disease (MCD), a major cause of nephrotic syndrome, is usually treated by corticosteroid administration. MCD unresponsiveness to therapy and recurrences are nonetheless frequently observed, particularly in adults. To explore MCD-related pathogenetic mechanisms and to ident...

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Detalles Bibliográficos
Autores principales: Eikrem, Øystein, Lillefosse, Bjørnar, Delaleu, Nicolas, Strauss, Philipp, Osman, Tarig, Vikse, Bjørn Egil, Debiec, Hanna, Ronco, Pierre, Sekulic, Miroslav, Koch, Even, Furriol, Jessica, Leh, Sabine Maria, Marti, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856051/
https://www.ncbi.nlm.nih.gov/pubmed/36672735
http://dx.doi.org/10.3390/biomedicines11010226