Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells

Small molecules are being used to inhibit cyclin dependent kinase (CDK) enzymes in cancer treatment. There is evidence that CDK is a drug-target for cancer therapy across many tumor types because it catalyzes the transfer of the terminal phosphate of ATP to a protein that acts as a substrate. Herein...

Descripción completa

Detalles Bibliográficos
Autores principales: Basappa, Basappa, Poonacha, Lisha K., Xi, Zhang, Vishwanath, Divakar, Yang, Ji-Rui, Nagaraja, Omantheswara, Swamynayaka, Ananda, Madegowda, Mahendra, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Gurudatt, Doddahosuru Mahadevappa, Pandey, Vijay, Shivananju, Nanjundaswamy, Ahn, Kwang Seok, Sethi, Gautam, Lobie, Peter E., Shubha, Priya Babu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856062/
https://www.ncbi.nlm.nih.gov/pubmed/36672680
http://dx.doi.org/10.3390/biomedicines11010172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856062/
https://www.ncbi.nlm.nih.gov/pubmed/36672680
http://dx.doi.org/10.3390/biomedicines11010172

Ejemplares similares