Mechanistic Insights and Potential Therapeutic Approaches in PolyQ Diseases via Autophagy

Polyglutamine diseases are a group of congenital neurodegenerative diseases categorized with genomic abnormalities in the expansion of CAG triplet repeats in coding regions of specific disease-related genes. Protein aggregates are the toxic hallmark for polyQ diseases and initiate neuronal death. Au...

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Detalles Bibliográficos
Autores principales: Jain, Mukul, Patil, Nil, Abdi, Gholamreza, Abbasi Tarighat, Maryam, Mohammed, Arifullah, Ahmad Mohd Zain, Muhammad Rajaei, Goh, Khang Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856063/
https://www.ncbi.nlm.nih.gov/pubmed/36672670
http://dx.doi.org/10.3390/biomedicines11010162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856063/
https://www.ncbi.nlm.nih.gov/pubmed/36672670
http://dx.doi.org/10.3390/biomedicines11010162

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