Lack of Epileptogenic Effects of the Creatine Precursor Guanidinoacetic Acid on Neuronal Cultures In Vitro

The creatine precursor Guanidinoacetic Acid (GAA) accumulates in the genetic deficiency of the GuanidinoAcetate Methyl Transferase (GAMT) enzyme and it is believed to cause the seizures that often occur in this condition. However, evidence that it is indeed epileptogenic is scarce and we previously...

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Detalles Bibliográficos
Autores principales: Poggio, Fabio, Brofiga, Martina, Tedesco, Mariateresa, Massobrio, Paolo, Adriano, Enrico, Balestrino, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856136/
https://www.ncbi.nlm.nih.gov/pubmed/36671459
http://dx.doi.org/10.3390/biom13010074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856136/
https://www.ncbi.nlm.nih.gov/pubmed/36671459
http://dx.doi.org/10.3390/biom13010074

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