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Protein Conformational Dynamics Underlie Selective Recognition of Thermophilic over Mesophilic Enzyme I by a Substrate Analogue
Substrate selectivity is an important preventive measure to decrease the possibility of cross interactions between enzymes and metabolites that share structural similarities. In addition, understanding the mechanisms that determine selectivity towards a particular substrate increases the knowledge b...
Autores principales: | Singh, Aayushi, Burns, Daniel, Sedinkin, Sergey L., Van Veller, Brett, Potoyan, Davit A., Venditti, Vincenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856155/ https://www.ncbi.nlm.nih.gov/pubmed/36671545 http://dx.doi.org/10.3390/biom13010160 |
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