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Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

It has been established for almost 30 years that the retinoic acid receptor (RAR) signalling pathway plays essential roles in the morphogenesis of a large variety of organs and systems. Here, we used a temporally controlled genetic ablation procedure to precisely determine the time windows requiring...

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Detalles Bibliográficos
Autores principales: Teletin, Marius, Mark, Manuel, Wendling, Olivia, Vernet, Nadège, Féret, Betty, Klopfenstein, Muriel, Herault, Yann, Ghyselinck, Norbert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856201/
https://www.ncbi.nlm.nih.gov/pubmed/36672706
http://dx.doi.org/10.3390/biomedicines11010198