Novel Hominid-Specific IAPP Isoforms: Potential Biomarkers of Early Alzheimer’s Disease and Inhibitors of Amyloid Formation

(1) Background and aims: Amyloidosis due to aggregation of amyloid-β (Aβ(42)) is a key pathogenic event in Alzheimer’s disease (AD), whereas aggregation of mature islet amyloid polypeptide (IAPP(37)) in human islets leads to β-cell dysfunction. The aim of this study is to uncover potential biomarker...

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Detalles Bibliográficos
Autores principales: Liu, Qing-Rong, Zhu, Min, Chen, Qinghua, Mustapic, Maja, Kapogiannis, Dimitrios, Egan, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856209/
https://www.ncbi.nlm.nih.gov/pubmed/36671553
http://dx.doi.org/10.3390/biom13010167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856209/
https://www.ncbi.nlm.nih.gov/pubmed/36671553
http://dx.doi.org/10.3390/biom13010167

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