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Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice

Hypertension may develop before or after the onset of diabetes and it is known to increase the risk of developing diabetic nephropathy. Alpha-1 antitrypsin (AAT) is a multi-functional protein with beneficial effects in various diseases but its role in reducing blood pressure in the diabetic kidney h...

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Detalles Bibliográficos
Autores principales: Lugo, Carlos I., Liu, Lauren P., Bala, Niharika, Morales, Angelica G., Gholam, Mohammed F., Abchee, Julia C., Elmoujahid, Nasseem, Elshikha, Ahmed Samir, Avdiaj, Rigena, Searcy, Louis A., Denslow, Nancy D., Song, Sihong, Alli, Abdel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856210/
https://www.ncbi.nlm.nih.gov/pubmed/36671451
http://dx.doi.org/10.3390/biom13010066