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Genetic Alterations in Members of the Proteasome 26S Subunit, AAA-ATPase (PSMC) Gene Family in the Light of Proteasome Inhibitor Resistance in Multiple Myeloma
SIMPLE SUMMARY: In comparison to other neoplasias, Multiple Myeloma is extremely sensitive to changes in protein homeostasis. Therefore, proteasome inhibitors are highly efficient and widely used for this disease. Genetic alterations of the PSMC genes, such as the ones shown in this manuscript, affe...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856285/ https://www.ncbi.nlm.nih.gov/pubmed/36672481 http://dx.doi.org/10.3390/cancers15020532 |