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Genetic Alterations in Members of the Proteasome 26S Subunit, AAA-ATPase (PSMC) Gene Family in the Light of Proteasome Inhibitor Resistance in Multiple Myeloma

SIMPLE SUMMARY: In comparison to other neoplasias, Multiple Myeloma is extremely sensitive to changes in protein homeostasis. Therefore, proteasome inhibitors are highly efficient and widely used for this disease. Genetic alterations of the PSMC genes, such as the ones shown in this manuscript, affe...

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Detalles Bibliográficos
Autores principales: Haertle, Larissa, Buenache, Natalia, Cuesta Hernández, Hipólito Nicolás, Simicek, Michal, Snaurova, Renata, Rapado, Inmaculada, Martinez, Nerea, López-Muñoz, Nieves, Sánchez-Pina, José María, Munawar, Umair, Han, Seungbin, Ruiz-Heredia, Yanira, Colmenares, Rafael, Gallardo, Miguel, Sanchez-Beato, Margarita, Piris, Miguel Angel, Samur, Mehmet Kemal, Munshi, Nikhil C., Ayala, Rosa, Kortüm, Klaus Martin, Barrio, Santiago, Martínez-López, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856285/
https://www.ncbi.nlm.nih.gov/pubmed/36672481
http://dx.doi.org/10.3390/cancers15020532