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Metabolic Adjustments following Glutaminase Inhibition by CB-839 in Glioblastoma Cell Lines

SIMPLE SUMMARY: Glioblastoma multiforme is the most common primary brain tumor. Unfortunately, it is also one of the cancer types that has the worst morbidity and mortality ratios, so new targets and treatments need to be found. The metabolism of glutamine is fundamental for the proliferation of man...

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Detalles Bibliográficos
Autores principales: De los Santos-Jiménez, Juan, Rosales, Tracy, Ko, Bookyung, Campos-Sandoval, José A., Alonso, Francisco J., Márquez, Javier, DeBerardinis, Ralph J., Matés, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856342/
https://www.ncbi.nlm.nih.gov/pubmed/36672480
http://dx.doi.org/10.3390/cancers15020531