E3 Ubiquitin Ligase TRIP12 Controls Exit from Mitosis via Positive Regulation of MCL-1 in Response to Taxol

SIMPLE SUMMARY: Taxol is a chemotherapy drug used in treatment of multiple cancers. Taxol works by blocking an essential process of cell division called mitosis. Although, Taxol treatment shows promise in fight against cancer, many patients eventually develop resistance. Loss of function mutations i...

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Detalles Bibliográficos
Autores principales: Keyan, Kripa S., Alanany, Rania, Kohil, Amira, Khan, Omar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856375/
https://www.ncbi.nlm.nih.gov/pubmed/36672454
http://dx.doi.org/10.3390/cancers15020505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856375/
https://www.ncbi.nlm.nih.gov/pubmed/36672454
http://dx.doi.org/10.3390/cancers15020505

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