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E3 Ubiquitin Ligase TRIP12 Controls Exit from Mitosis via Positive Regulation of MCL-1 in Response to Taxol
SIMPLE SUMMARY: Taxol is a chemotherapy drug used in treatment of multiple cancers. Taxol works by blocking an essential process of cell division called mitosis. Although, Taxol treatment shows promise in fight against cancer, many patients eventually develop resistance. Loss of function mutations i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856375/ https://www.ncbi.nlm.nih.gov/pubmed/36672454 http://dx.doi.org/10.3390/cancers15020505 |