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Consecutive Injection of High-Dose Lipopolysaccharide Modulates Microglia Polarization via TREM2 to Alter Status of Septic Mice

Background: The neuroinflammation of the central nervous system (CNS) is a prevalent syndrome of brain dysfunction secondary to severe sepsis and is regulated by microglia. Triggering the receptor expressed on myeloid cells 2 (TREM2) is known to have protective functions that modulate the microglial...

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Detalles Bibliográficos
Autores principales: Qiu, Zhiyun, Wang, Huilin, Qu, Mengdi, Zhu, Shuainan, Zhang, Hao, Liao, Qingwu, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856382/
https://www.ncbi.nlm.nih.gov/pubmed/36672106
http://dx.doi.org/10.3390/brainsci13010126