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Comparison of Mitochondrial Adenosine Triphosphate–Sensitive Potassium Channel High- vs Low-Affinity Sulfonylureas and Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With Metformin

IMPORTANCE: Sulfonylureas are frequently used as add-on to metformin in type 2 diabetes (T2D), and individual sulfonylurea agents carry different risks of cardiovascular disease. Sulfonylureas’ different affinities to cardiac mitochondrial adenosine triphosphate–sensitive potassium (mitoK(ATP)) chan...

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Detalles Bibliográficos
Autores principales: Wang, Meng-Ting, Pan, Hsueh-Yi, Huang, Ya-Ling, Wu, Li-Wei, Wang, Pin-Chun, Hsu, Yu-Juei, Lin, Tzu-Chieh, Lin, ChenWei, Lai, Jyun-Heng, Lee, Chien-Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856426/
https://www.ncbi.nlm.nih.gov/pubmed/36484988
http://dx.doi.org/10.1001/jamanetworkopen.2022.45854