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The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma

Post-therapeutic relapse, poor survival rates and increasing incidence justify the search for novel therapeutic targets and strategies in cutaneous malignant melanoma (CMM). Within this context, a potential oncogenic role for TrkA in CMM is suggested by reports of NTRK1 amplification, enhanced TrkA...

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Detalles Bibliográficos
Autores principales: Cappabianca, Lucia, Zelli, Veronica, Pellegrini, Cristina, Sebastiano, Michela, Maccarone, Rita, Clementi, Marco, Chiominto, Alessandro, Ruggeri, Pierdomenico, Cardelli, Ludovica, Ruggieri, Marianna, Sbaffone, Maddalena, Fargnoli, Maria-Concetta, Guadagni, Stefano, Farina, Antonietta R., Mackay, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856487/
https://www.ncbi.nlm.nih.gov/pubmed/36672171
http://dx.doi.org/10.3390/cells12020237