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Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer

IMPORTANCE: The E-cadherin gene, CDH1, and the α-E-catenin gene, CTNNA1, were previously identified as hereditary diffuse gastric cancer (HDGC) susceptibility genes, explaining 25% to 50% of HDGC cases. The genetic basis underlying disease susceptibility in the remaining 50% to 75% of patients with...

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Detalles Bibliográficos
Autores principales: Liu, Ze-Xian, Zhang, Xiao-Long, Zhao, Qi, Chen, Yungchang, Sheng, Hui, He, Cai-Yun, Sun, Yu-Ting, Lai, Ming-Yu, Wu, Min-Qing, Zuo, Zhi-Xiang, Wang, Wei, Zhou, Zhi-Wei, Wang, Feng-Hua, Li, Yu-Hong, Xu, Rui-Hua, Qiu, Miao-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856492/
https://www.ncbi.nlm.nih.gov/pubmed/36484990
http://dx.doi.org/10.1001/jamanetworkopen.2022.45836