Cargando…

Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer

IMPORTANCE: The E-cadherin gene, CDH1, and the α-E-catenin gene, CTNNA1, were previously identified as hereditary diffuse gastric cancer (HDGC) susceptibility genes, explaining 25% to 50% of HDGC cases. The genetic basis underlying disease susceptibility in the remaining 50% to 75% of patients with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ze-Xian, Zhang, Xiao-Long, Zhao, Qi, Chen, Yungchang, Sheng, Hui, He, Cai-Yun, Sun, Yu-Ting, Lai, Ming-Yu, Wu, Min-Qing, Zuo, Zhi-Xiang, Wang, Wei, Zhou, Zhi-Wei, Wang, Feng-Hua, Li, Yu-Hong, Xu, Rui-Hua, Qiu, Miao-Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856492/ https://www.ncbi.nlm.nih.gov/pubmed/36484990 http://dx.doi.org/10.1001/jamanetworkopen.2022.45836

Ejemplares similares

Identification of Novel EXT Mutations in Patients with Hereditary Multiple Exostoses Using Whole‐Exome Sequencing
por: Liang, Chao, et al.
Publicado: (2020)

Whole-Exome Sequencing Among School-Aged Children With High Myopia
por: Yu, Xiangyi, et al.
Publicado: (2023)

Whole exome sequencing for diagnosis of hereditary thrombocytopenia
por: Mekchay, Ponthip, et al.
Publicado: (2020)

Whole-exome sequencing identified four loci influencing craniofacial morphology in northern Han Chinese
por: Wu, Wei, et al.
Publicado: (2019)

Whole-exome sequencing identifies prognostic mutational signatures in gastric cancer
por: Zhu, Zhenxin, et al.
Publicado: (2020)

Genomic alterations in gastric cancers discovered via whole-exome sequencing
por: Zhang, Jie, et al.
Publicado: (2018)

Whole-Exome Sequencing and Targeted Copy Number Analysis in Primary Ciliary Dyskinesia
por: Marshall, Christian R., et al.
Publicado: (2015)

Challenges in Whole Exome Sequencing: An Example from Hereditary Deafness
por: Sirmaci, Asli, et al.
Publicado: (2012)

A three-caller pipeline for variant analysis of cancer whole-exome sequencing data
por: Liu, Ze-Kun, et al.
Publicado: (2017)

Whole-exome sequencing study of hypospadias
por: Chen, Zhongzhong, et al.
Publicado: (2023)

Comparison of prognostic nomograms based on different nodal staging systems in patients with resected gastric cancer
por: Wang, Zi-Xian, et al.
Publicado: (2017)

Multi‐genic pattern found in rare type of hypopituitarism: a whole‐exome sequencing study of Han Chinese with pituitary stalk interruption syndrome
por: Guo, Qing‐Hua, et al.
Publicado: (2017)

Tumor Mutational Burden and Genomic Alterations in Chinese Small Cell Lung Cancer Measured by Whole-Exome Sequencing
por: Su, Shan, et al.
Publicado: (2019)

Investigation of Genetic Mutations in High-risk and Low-risk Basal Cell Carcinoma in a Non-Caucasian Population by Whole Exome Sequencing
por: KIM, Hyun Jee, et al.
Publicado: (2021)

Whole-Exome Sequencing for Identifying Genetic Causes of Intellectual Developmental Disorders
por: Guo, Yu-Xiong, et al.
Publicado: (2021)

Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study
por: Fewings, Eleanor, et al.
Publicado: (2018)

Prognostic effects of 25-hydroxyvitamin D levels in gastric cancer
por: Ren, Chao, et al.
Publicado: (2012)

Identification of risk genes in Chinese nonobstructive azoospermia patients based on whole-exome sequencing
por: Liu, Yu-Jun, et al.
Publicado: (2022)

Whole-Exome Sequencing of Germline Variants in Non-BRCA Families with Hereditary Breast Cancer
por: Liu, Yaxuan, et al.
Publicado: (2022)

Whole-exome sequencing prioritizes candidate genes for hereditary cataract in the Emory mouse mutant
por: Bennett, Thomas M, et al.
Publicado: (2023)

Whole exome sequencing of Rett syndrome-like patients reveals the mutational diversity of the clinical phenotype
por: Lucariello, Mario, et al.
Publicado: (2016)

Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse
por: Sun, Miao, et al.
Publicado: (2012)

Novel Resistance Mechanisms to Osimertinib Analysed by Whole-Exome Sequencing in Non-Small Cell Lung Cancer
por: Wu, Zhen, et al.
Publicado: (2021)

Whole-Genome Sequencing of a Canine Family Trio Reveals a FAM83G Variant Associated with Hereditary Footpad Hyperkeratosis
por: Sayyab, Shumaila, et al.
Publicado: (2016)

Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma
por: Qiu, Miao-zhen, et al.
Publicado: (2010)

Identification of autism-related MECP2 mutations by whole-exome sequencing and functional validation
por: Wen, Zhu, et al.
Publicado: (2017)

Benchmarking of Whole Exome Sequencing and Ad Hoc Designed Panels for Genetic Testing of Hereditary Cancer
por: Feliubadaló, Lídia, et al.
Publicado: (2017)

Identification of a Novel Mutation of β-Spectrin in Hereditary Spherocytosis Using Whole Exome Sequencing
por: Bogusławska, Dżamila M., et al.
Publicado: (2021)

Characteristics and Research Waste Among Randomized Clinical Trials in Gastric Cancer
por: Lu, Jun, et al.
Publicado: (2021)

A short guide to hereditary diffuse gastric cancer
por: Guilford, Parry, et al.
Publicado: (2007)

Prophylactic Total Gastrectomy for Hereditary Diffuse Gastric Cancer
por: Shepard, Benjamin, et al.
Publicado: (2016)

Hereditary diffuse gastric cancer: One family’s story
por: Zylberberg, Haley M, et al.
Publicado: (2018)

Hereditary Diffuse Gastric Cancer: A 2022 Update
por: Kole, Christo, et al.
Publicado: (2022)

Whole-exome sequencing identified genes known to be responsible for retinitis pigmentosa in 28 Chinese families
por: Shen, Chang, et al.
Publicado: (2022)

Whole-exome sequencing in deceased fetuses with ultrasound anomalies: a retrospective analysis
por: Huang, Wei, et al.
Publicado: (2023)

Specific genetic aberrations of parathyroid in Chinese patients with tertiary hyperparathyroidism using whole-exome sequencing
por: Li, Lei, et al.
Publicado: (2023)

Whole Exome Sequencing Study Suggests an Impact of FANCA, CDH1 and VEGFA Genes on Diffuse Gastric Cancer Development
por: Nurgalieva, Alfiia, et al.
Publicado: (2023)

Implantation metastasis from sigmoid colon cancer to rectal anastomosis proved by whole exome sequencing and lineage inference for cancer heterogeneity and evolution analysis: Case report and literature review
por: Yu, Guan Yu, et al.
Publicado: (2022)

Whole-Exome Sequencing Identifies Novel Somatic Mutations in Chinese Breast Cancer Patients
por: Zhang, Yanfeng, et al.
Publicado: (2015)

Prognostic value of preoperative serum lactate dehydrogenase levels for resectable gastric cancer and prognostic nomograms
por: Wang, Zi-Xian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_v3ik688npg6umoa8lfnqr9753n