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Evaluation of Microsatellite Instability Molecular Analysis versus Immuno-Histochemical Interpretation in Malignant Neoplasms with Different Localizations

SIMPLE SUMMARY: Mismatch repair (MMR) system deficiency results in increased mutation rates with consequent microsatellite instability (MSI) and susceptibility to carcinogenesis. Clinically, testing MSI status contributes not only to early Lynch syndrome detection, which is associated with an increa...

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Detalles Bibliográficos
Autores principales: Sfakianaki, Maria, Tzardi, Maria, Tsantaki, Konstantina, Koutoulaki, Chara, Messaritakis, Ippokratis, Datseri, Galateia, Moustou, Eleni, Mavroudis, Dimitrios, Souglakos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856558/
https://www.ncbi.nlm.nih.gov/pubmed/36672302
http://dx.doi.org/10.3390/cancers15020353