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Therapeutic Targeting of Cancer-Associated Fibroblasts in the Non-Small Cell Lung Cancer Tumor Microenvironment

SIMPLE SUMMARY: In the tumor microenvironment, cancer-associated fibroblasts (CAFs) have multiple tumor-promoting functions in drug resistance, regulation of the niche of cancer stem cells and formation of the immunosuppressive network. Multiple mechanisms are involved, including production of growt...

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Detalles Bibliográficos
Autores principales: Shintani, Yasushi, Kimura, Toru, Funaki, Soichiro, Ose, Naoko, Kanou, Takashi, Fukui, Eriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856659/
https://www.ncbi.nlm.nih.gov/pubmed/36672284
http://dx.doi.org/10.3390/cancers15020335