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Relocalization of Translation Termination and Ribosome Recycling Factors to Stress Granules Coincides with Elevated Stop-Codon Readthrough and Reinitiation Rates upon Oxidative Stress

Upon oxidative stress, mammalian cells rapidly reprogram their translation. This is accompanied by the formation of stress granules (SGs), cytoplasmic ribonucleoprotein condensates containing untranslated mRNA molecules, RNA-binding proteins, 40S ribosomal subunits, and a set of translation initiati...

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Detalles Bibliográficos
Autores principales: Makeeva, Desislava S., Riggs, Claire L., Burakov, Anton V., Ivanov, Pavel A., Kushchenko, Artem S., Bykov, Dmitri A., Popenko, Vladimir I., Prassolov, Vladimir S., Ivanov, Pavel V., Dmitriev, Sergey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856671/
https://www.ncbi.nlm.nih.gov/pubmed/36672194
http://dx.doi.org/10.3390/cells12020259