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Notch Blockade Specifically in Bone Marrow-Derived FSP-1-Positive Cells Ameliorates Renal Fibrosis

Background: The infiltration of inflammatory cells during a kidney injury stimulates myofibroblast activation leading to kidney fibrosis. Fibroblast-specific protein 1 (FSP-1) positive cells have been reported as either myofibroblasts or monocytes during tissue fibrosis. The functions of FSP-1(+) ce...

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Detalles Bibliográficos
Autores principales: Wu, Yongdong, Liang, Ming, Huang, Fengzhang, Cheng, Owen H., Xiao, Xiaoguang, Lee, Tae Hoon, Truong, Luan, Cheng, Jizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856686/
https://www.ncbi.nlm.nih.gov/pubmed/36672147
http://dx.doi.org/10.3390/cells12020214