AtomNet-Aided OTUD7B Inhibitor Discovery and Validation

SIMPLE SUMMARY: Protein deubiquitinases are an important family of enzymes commonly deregulated in cancer. However, few deubiquitinase inhibitors have been identified and used in cancer treatment. Here, using an artificial intelligence (AI) AtomNet guided screening pipeline, we searched 4 million co...

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Detalles Bibliográficos
Autores principales: Chen, Jianfeng, Bolhuis, Derek L., Laggner, Christian, Kong, Deyu, Yu, Le, Wang, Xiaodong, Emanuele, Michael J., Brown, Nicholas G., Liu, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856706/
https://www.ncbi.nlm.nih.gov/pubmed/36672466
http://dx.doi.org/10.3390/cancers15020517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856706/
https://www.ncbi.nlm.nih.gov/pubmed/36672466
http://dx.doi.org/10.3390/cancers15020517

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