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TRIM10 Is Downregulated in Acute Myeloid Leukemia and Plays a Tumor Suppressive Role via Regulating NF-κB Pathway

SIMPLE SUMMARY: Acute myeloid leukemia (AML) remains an incurable hematological malignancy and patients have short survival due to AML relapse. In this study, we identified that TRIM10 was most downregulated in AML cell lines and AML patients. We further found that TRIM10 inhibits the growth of AML...

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Detalles Bibliográficos
Autores principales: Li, Lin, Li, Qi, Zou, Zhengrong, Huang, Zoufang, Chen, Yijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856727/
https://www.ncbi.nlm.nih.gov/pubmed/36672365
http://dx.doi.org/10.3390/cancers15020417