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DHODH Inhibition Exerts Synergistic Therapeutic Effect with Cisplatin to Induce Ferroptosis in Cervical Cancer through Regulating mTOR Pathway
SIMPLE SUMMARY: Ferroptosis exhibits potent antitumor ability and dihydroorotate dehydrogenase (DHODH) has recently been identified as a novel ferroptosis defender independently of GPX4 or FSP1. DHODH has been studied in several diseases including oral squamous cell carcinoma and small cell lung can...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856746/ https://www.ncbi.nlm.nih.gov/pubmed/36672495 http://dx.doi.org/10.3390/cancers15020546 |