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Resolvin D2 Reduces Chronic Neuropathic Pain and Bone Cancer Pain via Spinal Inhibition of IL-17 Secretion, CXCL1 Release and Astrocyte Activation in Mice

Chronic pain burdens patients and healthcare systems worldwide. Pain control remains urgently required. IL-17 (interleukin-17)-mediated neuroinflammation is of unique importance in spinal nociceptive transduction in pathological pain development. Recently, resolvin D2 (RvD2), as a bioactive, special...

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Detalles Bibliográficos
Autores principales: Pang, Jun, Xin, Pengfei, Kong, Ying, Wang, Zhe, Wang, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856778/
https://www.ncbi.nlm.nih.gov/pubmed/36672133
http://dx.doi.org/10.3390/brainsci13010152