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Relative Risk of Bladder and Kidney Cancer in Lynch Syndrome: Systematic Review and Meta-Analysis

SIMPLE SUMMARY: Lynch syndrome (LS) is an autosomal dominant hereditary disorder characterised by germline mutation in one of the four DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, PMS2) or deletion of the EPCAM gene. LS predisposes affected individuals to an increased lifetime risk of colorect...

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Detalles Bibliográficos
Autores principales: Nassour, Anthony-Joe, Jain, Anika, Hui, Nicholas, Siopis, George, Symons, James, Woo, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856836/
https://www.ncbi.nlm.nih.gov/pubmed/36672455
http://dx.doi.org/10.3390/cancers15020506