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Schlafen 12 Slows TNBC Tumor Growth, Induces Luminal Markers, and Predicts Favorable Survival

SIMPLE SUMMARY: This study indicates that we could develop a prognostic predictor and new targets for TNBC treatment by increasing the expression levels of the protein SLFN12 and through targeting the SLFN12 gene signature. Therapies that would target SLFN12 and its corresponding gene signature coul...

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Detalles Bibliográficos
Autores principales: Singhal, Sandeep K., Al-Marsoummi, Sarmad, Vomhof-DeKrey, Emilie E., Lauckner, Bo, Beyer, Trysten, Basson, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856841/
https://www.ncbi.nlm.nih.gov/pubmed/36672349
http://dx.doi.org/10.3390/cancers15020402