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Chromatin and Cancer: Implications of Disrupted Chromatin Organization in Tumorigenesis and Its Diversification

SIMPLE SUMMARY: Human DNA is ~2 m long, but is efficiently packaged in cell nucleus that is a million times smaller. The concerted action of several enzymes enables this packaging through hierarchical folding of DNA. These enzymes deposit unique marks on the DNA and DNA-binding proteins collectively...

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Detalles Bibliográficos
Autores principales: Sehgal, Poonam, Chaturvedi, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856863/
https://www.ncbi.nlm.nih.gov/pubmed/36672415
http://dx.doi.org/10.3390/cancers15020466