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Chromatin and Cancer: Implications of Disrupted Chromatin Organization in Tumorigenesis and Its Diversification
SIMPLE SUMMARY: Human DNA is ~2 m long, but is efficiently packaged in cell nucleus that is a million times smaller. The concerted action of several enzymes enables this packaging through hierarchical folding of DNA. These enzymes deposit unique marks on the DNA and DNA-binding proteins collectively...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856863/ https://www.ncbi.nlm.nih.gov/pubmed/36672415 http://dx.doi.org/10.3390/cancers15020466 |