Dietary Zinc Differentially Regulates the Effects of the GPR39 Receptor Agonist, TC-G 1008, in the Maximal Electroshock Seizure Test and Pentylenetetrazole-Kindling Model of Epilepsy

The G-protein coupled receptor 39 (GPR39) is gaining increasing attention as a target for future drugs, yet there are gaps in the understanding of its pharmacology. Zinc is an endogenous agonist or an allosteric modulator, while TC-G 1008 is a synthetic, small molecule agonist. Zinc is also a positi...

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Detalles Bibliográficos
Autores principales: Doboszewska, Urszula, Socała, Katarzyna, Pieróg, Mateusz, Nieoczym, Dorota, Sawicki, Jan, Sajnóg, Adam, Szewczyk, Bernadeta, Mlyniec, Katarzyna, Sowa, Ireneusz, Barałkiewicz, Danuta, Wlaź, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856893/
https://www.ncbi.nlm.nih.gov/pubmed/36672199
http://dx.doi.org/10.3390/cells12020264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856893/
https://www.ncbi.nlm.nih.gov/pubmed/36672199
http://dx.doi.org/10.3390/cells12020264

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