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Dietary Zinc Differentially Regulates the Effects of the GPR39 Receptor Agonist, TC-G 1008, in the Maximal Electroshock Seizure Test and Pentylenetetrazole-Kindling Model of Epilepsy
The G-protein coupled receptor 39 (GPR39) is gaining increasing attention as a target for future drugs, yet there are gaps in the understanding of its pharmacology. Zinc is an endogenous agonist or an allosteric modulator, while TC-G 1008 is a synthetic, small molecule agonist. Zinc is also a positi...
Autores principales: | Doboszewska, Urszula, Socała, Katarzyna, Pieróg, Mateusz, Nieoczym, Dorota, Sawicki, Jan, Sajnóg, Adam, Szewczyk, Bernadeta, Mlyniec, Katarzyna, Sowa, Ireneusz, Barałkiewicz, Danuta, Wlaź, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856893/ https://www.ncbi.nlm.nih.gov/pubmed/36672199 http://dx.doi.org/10.3390/cells12020264 |
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