Retinoic Acid Signalling in the Pineal Gland Is Conserved across Mammalian Species and Its Transcriptional Activity Is Inhibited by Melatonin

The pineal gland is integral to the circadian timing system due to its role in nightly melatonin production. Retinoic acid (RA) is a potent regulator of gene transcription and has previously been found to exhibit diurnal changes in synthesis and signalling in the rat pineal gland. This study investi...

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Detalles Bibliográficos
Autores principales: Ashton, Anna, Clark, Jason, Fedo, Julia, Sementilli, Angelo, Fragoso, Yara D., McCaffery, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856906/
https://www.ncbi.nlm.nih.gov/pubmed/36672220
http://dx.doi.org/10.3390/cells12020286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856906/
https://www.ncbi.nlm.nih.gov/pubmed/36672220
http://dx.doi.org/10.3390/cells12020286

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