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Distinct Cellular Origins and Differentiation Process Account for Distinct Oncogenic and Clinical Behaviors of Leiomyosarcomas

SIMPLE SUMMARY: Leiomyosarcomas are aggressive diseases mainly treated by surgical resection with or without conventional chemotherapy. Despite efforts to stratify patients, no targeted therapy nor immunotherapy has shown a major therapeutic effect. The oncogenesis of leiomyosarcoma is poorly unders...

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Detalles Bibliográficos
Autores principales: Darbo, Elodie, Pérot, Gaëlle, Darmusey, Lucie, Le Guellec, Sophie, Leroy, Laura, Gaston, Laëtitia, Desplat, Nelly, Thébault, Noémie, Merle, Candice, Rochaix, Philippe, Valentin, Thibaud, Ferron, Gwenaël, Chevreau, Christine, Bui, Binh, Stoeckle, Eberhard, Ranchere-Vince, Dominique, Méeus, Pierre, Terrier, Philippe, Piperno-Neumann, Sophie, Collin, Françoise, De Pinieux, Gonzague, Duffaud, Florence, Coindre, Jean-Michel, Blay, Jean-Yves, Chibon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856933/
https://www.ncbi.nlm.nih.gov/pubmed/36672483
http://dx.doi.org/10.3390/cancers15020534